Uma Thurman‘s one-scene appearance in Lars von Trier’s Nymphomaniac may be the most memorable moment in a film already chockablock with delights. (Fizzled-out threeways! Pitiless spanking! Getting peed on by Shia LaBeouf!) In the chapter simply titled “Mrs. H,” she arrives to find her husband in flagrante delicto with our gal Joe and proceeds to lose her dang mind, screaming her lungs out and bellowing for her children to come see their father in the whoring bed. It‘s an over-the-top moment that starts sad, progresses into discomfort, and ends with cruel hilarity — and it looks like Thurman may deliver more of that unhinged go-for-broke acting sometime soon.

Variety reported today that Thurman and character actress Siobhan Fallon Hogan have signed on to star in von Trier’s next film, the serial killer thriller The House That Jack Built. They’ll act alongside elder statesman of German cinema Bruno Ganz as well as starlet du jour Riley Keough, though neither actress’ role has been clarified as of yet. Hogan has collaborated with von Trier in the past, too, having appeared in his awards-winners Dancer in the Dark and Dogville. When working with Lars von Trier, it‘s generally for the best to bring in someone who knows what to expect from the notorious director, so maybe that’s a wise move.

While he was at it, von Trier also dropped a characteristically bleak soundbite about what audiences can expect from his new film. Making his elevator-to-hell pitch, he explained that the film will celebrate “the idea that life is evil and soulless, which is sadly proven by the recent rise of the Homo trumpus – the rat king.” Harsh words, but who knows evil and soullessness better than the guy who mutilated Charlotte Gainsbourg and Willem Dafoe’s genitals in Antichrist?

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